Lyrics:

Well you know blues overtook me when I was a little child
Now the world is my home, mile after mile
Now people let me tell you where highway 61 runs
It runs from my back door down to the setting sun

Well, when I go down to the river
Thats when I like to be alone
Blues is my companion, and a friend I've always known
Well I look into the sky, but there's cloud behind my eyes
Blues is my companion though my soul has survived

Well highway 61 is where blues was given birth
And your soul can catch a feeling rising up from mother earth
Well you'll never be the same, and you'll never be alone
And the blues is your companion, and the world is your own